The Inter-departmental Commission of Sustainable Development (ICSD) fulfils the role of fostering horizontal integration as laid out in the NSDS. It is composed of representatives of each ministry and can, on an ad-hoc basis, ask for advice from external experts.

In May 2016, the Government Council agreed on a renewed composition of the grand-ducal regulation regarding composition, organisation and functioning of the Commission with the objective having appropriate organizational structures to ensure the implementation of the goals and targets of the 2030 Agenda for Sustainable Development.